Biological Microscopes

Manipulating cells.

Micromanipulation system/ON3
Olympus' original micromanipulator offers high stability and excellent stability because of its compact body. Motorized coarse and oil hydraulic fine three axes operation are designed in its compact and rigid body with hanging down ergonomic joystick control. ON3 micromanipulator is securely fixed through the screw holes on IX2 microscope frame.

ON3-99D	ON3-99D with return mechanism (UT-R)
Manual combination (ONM-2D+ONO-301D+UT-D)	Manual combination with return mechanism (ONM-2D+ONO-301D+UT-D+UT-R)

Simultaneous laser light stimulation and imaging.

Confocal laser scanning microscope / FV1000 FLUOVIEW system
The Fluoview/FV1000 is a next-generation imaging system designed for high-resolution, confocal observation of both fixed and live cells. The FV1000 offers advances in confocal system performance while providing the speed and sensitivity required for live cell imaging with minimal risk of damage to living specimens. In addition, the FV1000 offers a revolutionary synchronized laser scanning system called the SIM Scanner. While one laser stimulates, the second laser simultaneously provides high resolution imaging. This coordination of laser stimulation and imaging makes the FV1000 an ideal choice for FRAP, FLIP and photoactivation.

Ultra-sensitive fluorescence microscopy.

TIRFM (Total Internal Reflection Fluorescence Microscopy System)
Since 1997, Olympus has been a market leader in objective based Total Internal Reflection microscope that allows an evanescent wave illumination approximately 200nm into the specimen beyond the coverglass interface. Olympus extends that leadership role by offering three objectives for TIRFM including the world's highest N.A. objective, the 100X N.A. 1.65 objective. The incredibly thin optical section created be TIRFM allows an extremely high signal to noise image to be collected. Popular applications include vesicle tracking, cellular adhesions and single molecule events.

• Once the initial alignment of the laser optical path is set, it is just simple operation switching between TIRF and widefield illumination.